1)
In infants and children with rickets and celiac disease.
2)
Inadvertent removal of the parathyroid gland during surgery on
the thyroid gland.
3)
In pyloric stenosis or hyperemesis from any cause which results
in high bicarbonate levels in plasma (alkalosis).
4)
In chronic diarrhoea , especially in sprue.
5)
In chronic interstitial nephritis.
6)
During lactation.
7)
In hysteria associated with excessive vomiting or emotional hyperpnoea.
In the normal subject, it may be brought on, by forced deep breathing
over a period of some minutes.
In
tetany or in alkalosis, this sign can be elicited by tying the
blood pressure cuff on the upper arm and raising the pressure
in the cuff above the systolic pressure and then maintaining it
for few minutes, when the hand develops the attitude of 'accoucheur's
hand'.
